Fluoxetine and its active metabolite norfluoxetine disrupt estrogen synthesis in a coculture model of the feto-placental unit. Hudon Thibeault AA, Laurent L, Vo Duy S, Sauvé S, Caron P, Guillemette C, Sanderson JT and Vaillancourt C. Mol Cell Endocrinology. Accepted.

Uric acid induces placental inflammation and alters trophoblast function via an IL-1-dependent pathway: implication for FGR. Brien ME, Duval C, Palacios J, Boufaied I, Hudon Thibault AA, Nadeau-Vallee M, Vaillancourt C, Sibley CP, Abrahams VM, Jones RL, Girard S. J of Immunology. Accepted.

Involvement of the IL-1β /CINC-1/MMP-10 axis in Group B Streptococcus-induced chorioamnionitis and subsequent fetal immune response syndrome (FIRS). Bergeron J, Gerges N, Guiraut C, Grbic D, Fortier LC, Vaillancourt C, Sébire G (2016) Placenta 47:116-123. PMID: 27780533

Sex determination in blue mussels: which method to choose?. Fraser M, Fortier M, Roumier PH, Parent L, Brousseau P, Fournier M, Surette C, Vaillancourt C. (2016) Mar Environ Res. Sep;120:78-85. doi: 10.1016/j.marenvres.2016.07.008. PMID: 27448778

Breast Feeding and Melatonin: Implications for Improving Perinatal Health. Anderson G, Vaillancourt C, Maes M, Reiter RJ. (2016) J Breastfeeding Bio 1 (1) 8-20

Alteration of placental type 2 11β-hydroxysteroid dehydrogenase expression and activity by lead. St-Pierre J, Fraser M, Vaillancourt C. (2016) Reprod Toxicol. Jul 22;65:133-138. doi: 10.1016/j.reprotox.2016.06.014. PMID: 27453427

In utero exposure to venlafaxine, a serotonin-norepinephrine reuptake inhibitor, increases cardiac anomalies and alters placental and heart serotonin signaling in the rat. Laurent L, Huang C, Ernest SR, Berard A, Vaillancourt C, Hales BF. (2016) [corresponding author CV] Birth Defects Res A Clin Mol Teratol. Jul 7. doi: 10.1002/bdra.23537. [Epub ahead of print] PMID: 27384265

Human primary trophoblast cell culture model to study the protective effects of melatonin against hypoxia/reoxygenation-induced placental disruption. Agrillo-Fagundes L, Clabault H, Laurent L, Hudon-Thibeault A, Assunção Salustiano E, Fortier M, Bienvenue-Pariseault J, Wong Yen P, Sanderson, T, Vaillancourt C. (2016) J Vis Exp. Jul 30;(113). DOI: 10.3791/54228. PMID: 27500522

Melatonin in Pregnancy: Effects on Brain Development and CNS Programming Disorders. Sagrillo-Fagundes L, Salustiano EM, Yen PW, Soliman A, Vaillancourt C. (2016) Current Pharmaceutical Design 22(8): 978 – 986. PMID: 26654775

Effects of prenatal maternal stress on serotonin and fetal development. St-Pierre J, Laurent L, King S, Vaillancourt C. (2016) Placenta. Dec 2. pii: S0143-4004(15)30094-1. doi: 10.1016/j.placenta.2015.11.013. [Epub ahead of print] PMID: 26691753

QF2011: A protocol to study the effects of the Queensland Flood on pregnant women, their pregnancies, and their children’s early development. King S, Kildea S, Austin M.P, Brunet A, Cobham VE, Dawson PA, Harris M, Hurrion EM, Laplante DP, McDermott BM, McIntyre HD, O’Hara MW, Schmitz N, Stapleton H, Tracy SK, Vaillancourt C, Dancause KN, Kruske S, Reilly N, Shoo L, Simcock G, Turcotte-Tremblay AM, & Yong Ping E. (2015) BMC Pregnancy and Childbirth. 15(1):109. PMID: 25943435


Placental melatonin system is present throughout pregnancy and regulates villous trophoblast differentiation. Soliman A, Lacasse AA, Lanoix D, Sagrillo-Fagundes L , Boulard V, Vaillancourt C. (2015) J Pineal Res. 59 (1), 38–46 PMID: 25833399

The activating effect of IFN-γ on monocytes/macrophages is regulated by the LIF-trophoblast-IL-10 axis via Stat1 inhibition and Stat3 activation. Dallagi A, Girouard J, Hamelin-Morrissette J, Dadzie R, Laurent L, Vaillancourt C, Lafond J, Reyes-Moreno. (2015) Cell Mol Immunol. 12(3):326-41. PMID: 25027966

The Serotonin 5-HT2A Receptor Antagonist Ritanserin Induces Apoptosis in Human Colorectal Cancer and Acts in Synergy with Curcumin. Ali Asghar Ahmadi, Mohammad Shadifar, Ramin Ataee, Vaillancourt C, Ataee A, Oufkir T, Jafari-Sabet M. (2015) Int Bio & Biomed J. 1 (2) (6-2015)


Immune response of blue mussels (Mytilus edulis) in spawning period following exposure to metals. Fraser M, Rault P, Fortier M, Brousseau P, Fournier M, Surette C, Vaillancourt C. (2014) J of Xenobiotics 4:4895, 65-57; DOI: 10.4081/xeno.2014.4895

Apoptosis is induced by curcumin in synergism with 5FU in human colorectal cancer cell line. Ataee R, Ahmadi AA, Shadifar M, Ataie A, Vaillancourt C, Jafari-Sabet M, Oufkir T. (2014) Sci-Afric Journal of Scientific Issues, Research and Essays Vol. 2 (4) 147-150. (ISSN 2311-6188)

Maternal and placental melatonin: Actions and implication for successful pregnancies. Sagrillo-Fagundes L, Soliman A, Vaillancourt C. (2014) Minerva ginecol;66:251-66 (ISSN 0026-4784) PMID: 24971781

A unique co-culture for fundamental and applied studies of human fetoplacental steroidogenesis and interference by environmental chemicals. Hudon Thibeault AA, Deroy K, Vaillancourt C and Sanderson T. (2014) Environ Health Perspect 122(4):371-7.[Drs Sanderson and Vaillancourt, both corresponding authors, contributed equally to this work.]. PMID: 24486430

First steps for integrating sex and gender considerations into basic experimental biomedical. Ritz SA, Antle DA, Côté J, Deroy K, Fraleigh N, Messing K, Parent L, St-Pierre J, Vaillancourt C, and Mergler D. (2014) FASEB J 28:4-13 – PMID:24056086


Decrease in phagocytosis capacity of hemocyte during spawning in Mytilus edulis: a pilot study. Fraser M, Rault P, Roumier PH, Fortier M, André C, Brousseau P, Gagné F, Fournier M, Surette C and Vaillancourt C. (2013) J of Xenobiotics 3(s1):e12/ doi:10.4081/xeno.2013.s1.e12

Novel role of the renin-angiotensin system in preeclampsia superimposed on chronic hypertension and the effects of exercise in a mouse model. Genest DS, Falcao S, Michel C, Kajla S, Germano MF, Lacasse AA, Vaillancourt C, Gutkowska J, and Lavoie JL. (2013) Hypertension 62:1055-1061. PMID: 24101664

Impact du contexte linguistique et culturel minoritaire sur le vécu de la grossesse. In suppl. La santé des populations de langue officielle en situation minoritaire. [Perception of the linguistic and cultural context minority on the lived experiences of pregnancy]. Lacaze-Masmonteil T, Lauriol E, Leis A, Normandeau J, Moreau D, Bouchard L, Vaillancourt C. (2013) Can J Public Health. 2013 Jun 7;104 (6 Suppl 1): 65-70. French. PMID: 24300325

Melatonin: the watchdog of villous trophoblast homeostasis against hypoxia/reoxygenation-induced oxidative stress and apoptosis. Lanoix D, Lacasse AA, Reiter J, Vaillancourt C. (2013) Mol Cell Endocrinol 381 : 35-45 – PMID: 23886990

Fish and seafood availability in markets in the Baie des Chaleurs region, New Brunswick, Canada: A heavy metal contamination baseline study. Fraser M, Surette C, Vaillancourt C. (2013) Environmental Sci. Pollution Res. 20 (2) 761-770 – PMID: 22961483


Placental Melatonin production and receptor expression are altered in preeclampsia: new insight on the role of this hormone in pregnancy. Lanoix D, Guérin P, Vaillancourt C. (2012) J Pineal Res. 53 : 417-425 -PMID: 22686298

Quantitative PCR pitfalls: the case of the human placenta. Lanoix D, Lacasse AA, St-Pierre J, Taylor SC, Ethier-Chiasson M, Lafond J and Vaillancourt C. (2012) Mol Biotechnol. 52(3) 234-243. DOI: 10.1007/s12033-012-9539-2.

Gestational Diabetes Affects Placental-Fetal Development. In : Pregnancy disorders and perinatal outocomes. Dubé E, Vaillancourt C, Lafond J, Belkacemi L. (2012) ebook publication, Bentham Science Publishers, Editors : J Lafond et C Vaillancourt. Chapter 6; 88-96

Stability of reference proteins in the human placenta: general protein stains are the benchmark. Lanoix D, St-Pierre J, Lacasse, AA, Viau M, Lafond J, Vaillancourt C. (2012) Placenta 33 (3) 151-156- PMID: 22244735

Placental Disorders in Preeclampsia: Maternal and Perinatal Outcomes. In : Pregnancy disorders and perinatal outocomes. Lanoix D, Haché S, Dubé E, Lafond J, Vaillancourt C. (2012) ebook publication, Bentham Science Publishers, Editors : J Lafond et C Vaillancourt. Chapter 7; 97-128.

Melatonin: The smart killer. The human trophoblast as a model. Lanoix D, Lacasse AA, Reiter RJ, Vaillancourt C. (2012) Molecular Cellular Endocrinology 348 : 1-11 – PMID: 21889572

Insulin-interfering hormones, nutrient metabolism and transport in placentas from gestational diabetic pregnancies. Belkacemi L, Vaillancourt C, Dubé E, Lafond J. (2012) In : Advances in Medicine and Biology. Vol. 44 pp. 165-180. Editors: Leon V. Berhardt, Nova Publishers. ISBN: 978-1-62100-909-2.

Pregnancy disorders and perinatal outocomes, ebook publication, Bentham Science Publishers, Editors : J Lafond et C Vaillancourt (eds). (2012) Bentham Science Publishers,US, eBooks, pp. 152. eISBN : 978-1-60805-372-8. DOI: 10.2174/97816080537281120101


Phosphorylation of JAK2 by serotonin 5-HT2A-receptor activates both STAT3 and ERK1/2 pathways and increases growth of JEG-3 human placental choriocarcinomal cell. Oufkir T and Vaillancourt C. (2011) Placenta 32 : 1033-1040 -PMID: 21993263

Stimulation of serotonergic 5-HT2A receptor signalling increases placental aromatase (CYP19) activity and expression in BeWo and JEG-3 human choriocarcinoma cells. Klempan TA, Hudon-Thibeault AA, Oukir T, Vaillancourt C, and Sanderson JT. (2011) Placenta. 32(9):651-6. [Drs Sanderson and Vaillancourt, both corresponding authors, contributed equally to this work.] – PMID: 21703684

Spatial and temporal distribution of heavy metal concentrations in mussels (Mytilus edulis) from the Baie des Chaleurs, New Brunswick, Canada. Fraser, M., Surette, C. and Vaillancourt, C. (2011) Marine Pollution Bulletin –Baseline paper. 62(6):1345-51. – PMID: 21507426

New intracellular and molecular aspects in pathophysiology of colorectal cancer. Ziapour P, Ataee R, Shadifar M, Vaillancourt C, Ahmadi A, Sabet MJ, Ataee A. (2011) Gastroenterology and Hepatology From Bed to Bench.4(2):43-52